Trabalhos Originais Archives - Revista Brasileira de Ginecologia e Obstetrícia
Summary
Rev Bras Ginecol Obstet. 1998;20(10):565-569
DOI 10.1590/S0100-72031998001000004
Purpose: to estimate the duration of cervical neoplasia from human pappilomavirus (HPV) infection to advanced invasive carcinoma, using as paremeter the mean age of the women at diagnosis. Methods: this cross-sectional study included 1,177 women with HPV infection, 1,561 with cervical intraepithelial neoplasia (CIN) and 773 with invasive carcinoma. Results: the mean ages of CIN 1 and CIN 2 on diagnosis were not statistically different. The mean duration of CIN 2 was 2.2 years. The mean duration of CIN 3 was 10.3 years, with 4.1 years as severe dysplasia and 6.2 years as carcinoma in situ (CIS). The mean duration of high grade squamous intraepithelial lesions was 12.5 years. The duration means of invasive carcinoma stages Ia, Ib and II were 3.0, 2.7 and 3.7 years, respectively. Conclusions: according to the results, CIN 1 and CIN 2 may arise directly from HPV infection and most of these lesions are transient. CIS presented the longest duration and the mean asymptomatic period of cervical neoplasia is 18.2 years. These results were discussed considering the present knowledge of the natural history of cervical carcinoma and other studies on duration of this neoplasia.
Summary
Rev Bras Ginecol Obstet. 1998;20(10):565-569
DOI 10.1590/S0100-72031998001000004
Purpose: to estimate the duration of cervical neoplasia from human pappilomavirus (HPV) infection to advanced invasive carcinoma, using as paremeter the mean age of the women at diagnosis. Methods: this cross-sectional study included 1,177 women with HPV infection, 1,561 with cervical intraepithelial neoplasia (CIN) and 773 with invasive carcinoma. Results: the mean ages of CIN 1 and CIN 2 on diagnosis were not statistically different. The mean duration of CIN 2 was 2.2 years. The mean duration of CIN 3 was 10.3 years, with 4.1 years as severe dysplasia and 6.2 years as carcinoma in situ (CIS). The mean duration of high grade squamous intraepithelial lesions was 12.5 years. The duration means of invasive carcinoma stages Ia, Ib and II were 3.0, 2.7 and 3.7 years, respectively. Conclusions: according to the results, CIN 1 and CIN 2 may arise directly from HPV infection and most of these lesions are transient. CIS presented the longest duration and the mean asymptomatic period of cervical neoplasia is 18.2 years. These results were discussed considering the present knowledge of the natural history of cervical carcinoma and other studies on duration of this neoplasia.
Summary
Rev Bras Ginecol Obstet. 1998;20(10):557-561
DOI 10.1590/S0100-72031998001000003
Purpose: the authors report their experience with necrotizing fasciitis (NF) cases which occurred in the Gynecology and Obstetrics Service of the Hospital de Clínicas de Porto Alegre, assessing the frequency of NF and analyzing the association between NF and certain risk factors cited in the literature. Methods: a retrospective study of patients a with diagnosis of necrotizing fasciitis at the Hospital de Clínicas de Porto Alegre from January 1990 to December 1997. Results: two post-cesarean section and one post-surgical (because of ectopic pregnancy) NF cases were found. None of the patients presented clinical complications nor NF risk factors and all surgeries were urgent. The NF frequency in this study was 2.6/10.000 cesarians and mortality was zero. Discussion: NF is a clinical syndrome which does not occur very often but is associated with high morbidity and mortality. This disease involves the surgical wound and the fascial plans. Fast handling and early and intensive treatment bring about good results and decrease in the mortality rate.
Summary
Rev Bras Ginecol Obstet. 1998;20(10):557-561
DOI 10.1590/S0100-72031998001000003
Purpose: the authors report their experience with necrotizing fasciitis (NF) cases which occurred in the Gynecology and Obstetrics Service of the Hospital de Clínicas de Porto Alegre, assessing the frequency of NF and analyzing the association between NF and certain risk factors cited in the literature. Methods: a retrospective study of patients a with diagnosis of necrotizing fasciitis at the Hospital de Clínicas de Porto Alegre from January 1990 to December 1997. Results: two post-cesarean section and one post-surgical (because of ectopic pregnancy) NF cases were found. None of the patients presented clinical complications nor NF risk factors and all surgeries were urgent. The NF frequency in this study was 2.6/10.000 cesarians and mortality was zero. Discussion: NF is a clinical syndrome which does not occur very often but is associated with high morbidity and mortality. This disease involves the surgical wound and the fascial plans. Fast handling and early and intensive treatment bring about good results and decrease in the mortality rate.