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  • Review Article

    Characterization of Placental Infection by Zika Virus in Humans: A Review of the Literature

    Revista Brasileira de Ginecologia e Obstetrícia. 2020;42(9):577-585

    Summary

    Review Article

    Characterization of Placental Infection by Zika Virus in Humans: A Review of the Literature

    Revista Brasileira de Ginecologia e Obstetrícia. 2020;42(9):577-585

    DOI 10.1055/s-0040-1712126

    Views9

    Abstract

    Objective

    The aim of the current review is to present a systematic evaluation of reported human placental findings in cases of zika virus (ZIKV) infection.

    Data

    sources We reviewed the EMBASE, PUBMED, and SCIELO databases until June 2019, without language restrictions. Selection of studies The search terms placenta AND zika virus were used. The inclusion criteria of the studies were studies that reported placental findings in humans. Experimental studies, reviews, notes or editorials were excluded. A total of 436 studies were retrieved; after duplicate exclusion, 243 articles had their titles screened, and 128 had their abstract read; of those, 32 were included in the final analysis (18 case reports, 10 case series, and 4 cohorts)

    Data collection

    We collected data concerning the author, year of publication, study design, number of participants, number of placental samples, onset of symptoms, perinatal outcomes, and main findings on histological analysis.

    Data synthesis

    The placental pathologic findings were described as mild and nonspecific, similar to those of other placental infections, including chronic placentitis, chronic villitis, increased Hofbauer cells, irregular fibrin deposits, increased mononuclear cells in the villus stroma, villous immaturity, edema, hypervascularization, stromal fibrosis, calcification, and focal necrosis of syncytiotrophoblasts.

    Conclusion

    Zika infection presents unspecific placental findings, similar to other infections in the toxoplasmosis, other agents, rubella, cytomegalovirus, and herpes (TORCH)group. Characterizing and standardizing placental findings after zika virus infection is key to understanding the mechanisms of congenital diseases.

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    Characterization of Placental Infection by Zika Virus in Humans: A Review of the Literature
  • Resumos de Teses

    Monitorização Ambulatorial da Pressão Arterial (Mapa) em Pacientes com Doença Hipertensiva Específica da Gestação: Correlação dos Achados com o Grau de Proteinúria

    Revista Brasileira de Ginecologia e Obstetrícia. 1998;20(10):577-578

    Summary

    Resumos de Teses

    Monitorização Ambulatorial da Pressão Arterial (Mapa) em Pacientes com Doença Hipertensiva Específica da Gestação: Correlação dos Achados com o Grau de Proteinúria

    Revista Brasileira de Ginecologia e Obstetrícia. 1998;20(10):577-578

    DOI 10.1590/S0100-72031998001000007

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    Monitorização Ambulatorial da Pressão Arterial (Mapa) em Pacientes com Doença Hipertensiva Específica da Gestação. Correlação dos Achados com o Grau de Proteinúria […]
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  • Resumos de Teses

    A Placenta da Gestante Diabética

    Revista Brasileira de Ginecologia e Obstetrícia. 1998;20(10):577-577

    Summary

    Resumos de Teses

    A Placenta da Gestante Diabética

    Revista Brasileira de Ginecologia e Obstetrícia. 1998;20(10):577-577

    DOI 10.1590/S0100-72031998001000006

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    A Placenta da Gestante Diabética […]
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  • Editorial

    Endometrial Cancer in Brazil: Preparing for the Rising Incidence

    Revista Brasileira de Ginecologia e Obstetrícia. 2018;40(10):577-579

    Summary

    Editorial

    Endometrial Cancer in Brazil: Preparing for the Rising Incidence

    Revista Brasileira de Ginecologia e Obstetrícia. 2018;40(10):577-579

    DOI 10.1055/s-0038-1673644

    Views4
    Brazil has a population of over 206 million people. It is estimated that there will be 6.22 new cases of endometrial cancer (EC) for every 100,000 Brazilian women in 2018. From the estimated 6,000 cases in 2016, GLOBOCAN predicts an increase to 9,372 new cases in 2025 and to 11,963 in 2035. Obesity and overweight […]
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  • Trabalhos Originais

    Correlation between the Doppler indices of inferior vena cava and ductus venosus and fetal umbilical cord blood concentration of hemoglobin in pregnant women with isoimmunization

    Revista Brasileira de Ginecologia e Obstetrícia. 2003;25(8):577-583

    Summary

    Trabalhos Originais

    Correlation between the Doppler indices of inferior vena cava and ductus venosus and fetal umbilical cord blood concentration of hemoglobin in pregnant women with isoimmunization

    Revista Brasileira de Ginecologia e Obstetrícia. 2003;25(8):577-583

    DOI 10.1590/S0100-72032003000800006

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    PURPOSE: to determine the relationship between the Doppler indices of inferior vena cava and ductus venosus and the fetal hemoglobin concentration. METHODS: a cross-sectional prospective study was performed at the "Centro de Medicina Fetal HC UFMG" from January 1998 to July 2001. Thirty-one pregnant women with isoimmunization, detected by an indirect Coombs test >1:8, underwent a protocol for the identification of fetal hemolysis. When intrauterine transfusions were indicated, the umbilical cord hemoglobin concentration was measured at the begining of the procedure. In the other cases, it was measured at delivery. Every single intrauterine transfusion preceded by Doppler flow velocity waveforms from inferior vena cava and ductus venosus was defined as one case. Hemocue® (B-Hemoglobin Photometer Hemocue AB; Angelholm, Sweden) was used to measure the fetal hemoglobin concentration. In all cases, inferior vena cava and ductus venosus Doppler examinations were performed before the collection of fetal blood samples. For the inferior vena cava Doppler, the studied indices were pulsatility index for veins (PVI), peak velocity index for veins (PVIV) and atrial/systole ratio (CA/SV ratio or preload index); for ductus venosus, PVI, PVIV and systole/atrial ratio (SV/CA ratio). The relationship between inferior vena cava and ductus venosus Doppler indices and cord blood hemoglobin concentration was obtained by simple linear regression analysis. Moreover, an association between those indices and the finding of fetal hemoglobin <10 g/dL was shown by the c² test, significant at p<0.05. RESULTS: seventy-four procedures were studied. In twenty-three cases fetal hemoglobin was below 7 g/dL. A significant negative correlation between all studied Doppler indices and fetal concentration of hemoglobin was observed (p<0.05). The highest Doppler index values were observed in severe anemic fetuses. Fetuses with cord blood hemoglobin below 10 g/dL presented inferior vena cava and ductus venosus Doppler indices over the 95 percentile for gestational age. CONCLUSIONS: Doppler flow velocity waveforms from inferior vena cava and ductus venosus may be used as a noninvasive marker of severe fetal anemia.

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  • Original Articles

    Reproductive outcome in pregnant women with recurrent pregnancy loss

    Revista Brasileira de Ginecologia e Obstetrícia. 2015;37(12):578-584

    Summary

    Original Articles

    Reproductive outcome in pregnant women with recurrent pregnancy loss

    Revista Brasileira de Ginecologia e Obstetrícia. 2015;37(12):578-584

    DOI 10.1590/SO100-720320150005445

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    Abstract

    PURPOSE:

    To estimate the future pregnancy success rate in women with a history of recurrent pregnancy loss.

    METHODS:

    A retrospective cohort study including 103 women seen at a clinic for recurrent pregnancy loss (loss group) between January 2006 and December 2010 and a control group including 204 pregnant women seen at a low-risk prenatal care unit between May 2007 and April 2008. Both groups were seen in the university teaching hospital the Maternidade Climério de Oliveira, Salvador, Bahia, Brazil. Reproductive success rate was defined as an alive-birth, independent of gestational age at birth and survival after the neonatal period. Continuous variables Means and standard deviations (SD) were compared using Student's t-test and nominal variables proportions by Pearson χ2test.

    RESULTS:

    Out of 90 who conceived, 83 (91.2%) had reproductive success rate. There were more full-term pregnancies in the control than in the loss group (174/187; 92.1 versus 51/90; 56.7%; p<0.01). The prenatal visits number was satisfactory for 76 (85.4%) women in the loss group and 125 (61.3%) in the control (p<0.01). In this, the beginning of prenatal care was earlier (13.3; 4.2 versus 19.6; 6.9 weeks). During pregnancy, the loss group women increased the weight more than those in the control group (58.1 versus 46.6%; p=0.04). Although cervix cerclage was performed in 32/90 women in the loss group, the pregnancy duration mean was smaller (34.8 weeks; SD=5.6 versus 39.3 weeks; SD=1.6; p<0.01) than in the control group. Due to gestational complications, cesarean delivery predominated in the loss group (55/83; 64.7 versus 73/183; 39.5%; p<0.01).

    CONCLUSION:

    A very good reproductive success rate can be attributed to greater availability of healthcare services to receive pregnant women, through prenatal visits (scheduled or not), cervical cerclage performed on time, and available hospital care for the mother and newborn.

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  • Letter to Editor

    Construct and Criterion Validity of the Postmenopause Sexuality Questionnaire-PMSQ

    Revista Brasileira de Ginecologia e Obstetrícia. 2021;43(7):578-578

    Summary

    Letter to Editor

    Construct and Criterion Validity of the Postmenopause Sexuality Questionnaire-PMSQ

    Revista Brasileira de Ginecologia e Obstetrícia. 2021;43(7):578-578

    DOI 10.1055/s-0041-1733910

    Views2
    Dear Editor, In 2020, we have published the article “Construct and criterion validity of the postmenopause sexuality questionnaire—PMSQ” (DOI: https://doi.org/10.1055/s-0040-1701461). Complete copies, in English and Portuguese, of the instrument were attached to be published as supplemental material. Nevertheless, the instrument was not published. Since we have been asked to send a copy of the questionnaire […]
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  • Letter to Editor Revista Brasileira de Ginecologia e Obstetrícia. 2021;43(7):578-578

    Summary

    Letter to Editor

    Revista Brasileira de Ginecologia e Obstetrícia. 2021;43(7):578-578

    DOI 10.1055/s-0041-1733910

    Views0
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