Artigos - Revista Brasileira de Ginecologia e Obstetrícia

Editorial
DECLARAÇÃO DE BARCELONA
Revista Brasileira de Ginecologia e Obstetrícia. 2002;24(3):151-151
27/06/2002

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This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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Editorial
DECLARAÇÃO DE BARCELONA
Revista Brasileira de Ginecologia e Obstetrícia. 2002;24(3):151-151
27/06/2002
DOI 10.1590/S0100-72032002000300001
Visualizações38
DECLARAÇÃO DE BARCELONA […]
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This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Editorial
A Grande Vitória
Revista Brasileira de Ginecologia e Obstetrícia. 2002;24(1):07-07
21/06/2002

Visualizações55

This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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Editorial
A Grande Vitória
Revista Brasileira de Ginecologia e Obstetrícia. 2002;24(1):07-07
21/06/2002
DOI 10.1590/S0100-72032002000100001
Visualizações55
A Grande Vitória[…]
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This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Trabalhos Originais
Carcinoma Microinvasor no Cone Pós Biópsia Dirigida Compatível com NIC 3
Revista Brasileira de Ginecologia e Obstetrícia. 2002;24(1):37-43
20/06/2002

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This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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Trabalhos Originais
Carcinoma Microinvasor no Cone Pós Biópsia Dirigida Compatível com NIC 3
Revista Brasileira de Ginecologia e Obstetrícia. 2002;24(1):37-43
20/06/2002
DOI 10.1590/S0100-72032002000100006
Priscila Garcia Figueiredo,
Renata Clementino Gontijo,
Sophie Françoise Mauricette Derchain,
Fabiana Yumi Nakano,
Julio César Teixeira,
Edson Zangiacomi Martinez
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Objetivo: determinar os fatores associados ao achado de carcinoma microinvasor no cone de mulheres com biópsia colpodirigida prévia compatível com neoplasia intra-epitelial cervical (NIC) 3 e avaliar a proporção de margens comprometidas. Pacientes e Métodos: foram revisados os prontuários de 385 mulheres (média de idade: 39 anos) submetidas à conização a frio ou por cirurgia de alta freqüência (CAF) com alça no período de janeiro de 1993 a julho de 2000. Estes procedimentos foram indicados por biópsia compatível com NIC 3. Resultados: o diagnóstico do cone foi compatível com NIC 3 em 243 mulheres (63%) e com NIC 2 em 13 (3%). Apenas 10 apresentaram HPV/NIC 1 (3%) e oito não tinham doença residual no cone. Entretanto, 101 mulheres apresentaram carcinoma microinvasor no cone (26%) e 10 (3%) carcinoma invasor franco. A idade, o estado menstrual e o número de partos não estiveram relacionados com a gravidade da lesão no cone. Mulheres com alterações da colpocitologia oncológica sugestivas de invasão apresentaram um risco significativamente maior de apresentar carcinoma microinvasor ou invasor no histológico final (p<0,01), embora 52 das 243 mulheres com NIC 2 ou NIC 3 no cone também tivessem sugestão de invasão na colpocitologia. Entre as mulheres com NIC 2 ou 3, 44% apresentaram epitélio branco, 21% pontilhado e 17% mosaico. Esta proporção foi semelhante nas mulheres com carcinoma microinvasor ou invasor, sendo estas imagens encontradas, respectivamente, em 37%, 23% e 21%. O comprometimento das margens do cone foi significativamente maior nas mulheres submetidas a CAF (49%) do que naquelas submetidas à conização a frio (29%). Conclusão: a ausência de fatores independentes clínicos e colposcópicos que se associam com o achado de carcinomas microinvasivos em mulheres submetidas à conização por biópsia compatível com NIC 3 justifica a excisão cônica da junção escamo-colunar nas lesões cervicais de alto grau.

Palavras-chave: Carcinoma microinvasor Colposcopia Conização Neoplasia intra-epitelial
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Resumos de Teses
Contribuição ao Estudo do Laser de Vapor de Cobre no Tratamento da Endometriose Induzida Cirurgicamente em Coelhas
- Maurício Paulo Angelo Mieli
Revista Brasileira de Ginecologia e Obstetrícia. 2002;24(1):71-71
19/06/2002

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This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Resumo
Resumos de Teses
Contribuição ao Estudo do Laser de Vapor de Cobre no Tratamento da Endometriose Induzida Cirurgicamente em Coelhas
Revista Brasileira de Ginecologia e Obstetrícia. 2002;24(1):71-71
19/06/2002
DOI 10.1590/S0100-72032002000100017
Maurício Paulo Angelo Mieli
Visualizações33
Contribuição ao Estudo do Laser de Vapor de Cobre no Tratamento da Endometriose Induzida Cirurgicamente em Coelhas […]
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Resumos de Teses
Prevalência das Neoplasias Intra-epiteliais Cervicais e Lesões Induzidas pelo HPV nas Mulheres Soropositivas/AIDS
- Susana Cristina Aidé Viviani Fialho
Revista Brasileira de Ginecologia e Obstetrícia. 2002;24(1):70-70
19/06/2002

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This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Resumo
Resumos de Teses
Prevalência das Neoplasias Intra-epiteliais Cervicais e Lesões Induzidas pelo HPV nas Mulheres Soropositivas/AIDS
Revista Brasileira de Ginecologia e Obstetrícia. 2002;24(1):70-70
19/06/2002
DOI 10.1590/S0100-72032002000100015
Susana Cristina Aidé Viviani Fialho
Visualizações35
Prevalência das Neoplasias Intra-epiteliais Cervicais e Lesões Induzidas pelo HPV nas Mulheres Soropositivas/AIDS […]
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This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Resumos de Teses
Avaliação do Potencial de Peroxidação Lipídica no Fluido Peritoneal de Mulheres Inférteis com Endometriose Pélvica
- Vivian Ferreira do Amaral
Revista Brasileira de Ginecologia e Obstetrícia. 2002;24(1):70-70
19/06/2002

Visualizações31

This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Resumo
Resumos de Teses
Avaliação do Potencial de Peroxidação Lipídica no Fluido Peritoneal de Mulheres Inférteis com Endometriose Pélvica
Revista Brasileira de Ginecologia e Obstetrícia. 2002;24(1):70-70
19/06/2002
DOI 10.1590/S0100-72032002000100016
Vivian Ferreira do Amaral
Visualizações31
Avaliação do Potencial de Peroxidação Lipídica no Fluido Peritoneal de Mulheres Inférteis com Endometriose Pélvica […]
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Resumos de Teses
Avaliação da Função Ovariana Pós-histerectomia Total Abdominal em Mulheres no Menacme
- Eliana Aguiar Petri Nahás
Revista Brasileira de Ginecologia e Obstetrícia. 2002;24(1):69-69
19/06/2002

Visualizações33

This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Resumo
Resumos de Teses
Avaliação da Função Ovariana Pós-histerectomia Total Abdominal em Mulheres no Menacme
Revista Brasileira de Ginecologia e Obstetrícia. 2002;24(1):69-69
19/06/2002
DOI 10.1590/S0100-72032002000100013
Eliana Aguiar Petri Nahás
Visualizações33
Avaliação da Função Ovariana Pós-histerectomia Total Abdominal em Mulheres no Menacme […]
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This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Resumos de Teses
Linfonodo Sentinela no Carcinoma Infiltrativo Inicial de Mama: Estudo de sua Localização e de sua Capacidade Preditiva em Relação ao Estado da Axila
- José Roberto Morales Piato
Revista Brasileira de Ginecologia e Obstetrícia. 2002;24(1):69-69
19/06/2002

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This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Resumo
Resumos de Teses
Linfonodo Sentinela no Carcinoma Infiltrativo Inicial de Mama: Estudo de sua Localização e de sua Capacidade Preditiva em Relação ao Estado da Axila
Revista Brasileira de Ginecologia e Obstetrícia. 2002;24(1):69-69
19/06/2002
DOI 10.1590/S0100-72032002000100014
José Roberto Morales Piato
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Linfonodo Sentinela no Carcinoma Infiltrativo Inicial de Mama: Estudo de sua Localização e de sua Capacidade Preditiva em Relação ao Estado da Axila […]
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Original Article
Sacral neuromodulation therapy for urinary and defecatory disorders: experience in a Latin American public hospital
- Marcelo Mass-Lindenbaum ,
- Diego Arévalo-Vega ,
- Isidora Aleuanlli ,
- Fernanda Santis-Moya ,
- Andrea Maluenda ,
- Javier Pizarro-Berdichevsky
Revista Brasileira de Ginecologia e Obstetrícia. 2024;46:e-rbgo11
00/00/2024

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This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Resumo
Original Article
Sacral neuromodulation therapy for urinary and defecatory disorders: experience in a Latin American public hospital
Revista Brasileira de Ginecologia e Obstetrícia. 2024;46:e-rbgo11
00/00/2024
DOI 10.61622/rbgo/2024AO11
Marcelo Mass-Lindenbaum ,
Diego Arévalo-Vega ,
Isidora Aleuanlli ,
Fernanda Santis-Moya ,
Andrea Maluenda ,
Eitan Dines ,
Miriam Cohen-Vaizer ,
Álvaro Saavedra ,
Trinidad Raby ,
Bernardita Blumel ,
Rodrigo Cuevas ,
Simone Pohlhammer ,
Gabriela Alarcon ,
Marco Arellano Albornoz ,
Javier Pizarro-Berdichevsky
Visualizações515
Abstract

Objective:

To show the experience of a Latin American public hospital, with SNM in the management of either OAB, NOUR or FI, reporting feasibility, short to medium-term success rates, and complications.

Methods:

A retrospective cohort was conducted using data collected prospectively from patients with urogynecological conditions and referred from colorectal surgery and urology services between 2015 and 2022.

Results:

Advanced or basic trial phases were performed on 35 patients, 33 (94%) of which were successful and opted to move on Implantable Pulse Generator (GG) implantation. The average follow-up time after definitive implantation was 82 months (SD 59). Of the 33 patients undergoing, 27 (81%)reported an improvement of 50% or more in their symptoms at last follow-up. Moreover, 30 patients (90%) with a definitive implant reported subjective improvement, with an average PGI-I “much better” and 9 of them reporting to be “excellent” on PGI-I.

Conclusion:

SNM is a feasible and effective treatment for pelvic floor dysfunction. Its implementation requires highly trained groups and innovative leadership. At a nation-wide level, greater diffusion of this therapy among professionals is needed to achieve timely referral of patients who require it.

Palavras-chave: Electric stimulation therapy fecal incontinence Incontinence Non-obstructive urinary retention overactive Sacral neuromodulation Urinary bladder
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This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Original Article
Real-world utilization pattern of dydrogesterone in 7287 Indian women with obstetric and gynecological conditions: data from multicentric, retrospective study
- Jaydeep Tank ,
- Sanjay Gupte ,
- Purna Chandra Mahapatra ,
- Jayanthi Reddy ,
- Pratima Mittal ,
- Onkar Swami
Revista Brasileira de Ginecologia e Obstetrícia. 2024;46:e-rbgo18
00/00/2024

Visualizações504

This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Resumo
Original Article
Real-world utilization pattern of dydrogesterone in 7287 Indian women with obstetric and gynecological conditions: data from multicentric, retrospective study
Revista Brasileira de Ginecologia e Obstetrícia. 2024;46:e-rbgo18
00/00/2024
DOI 10.61622/rbgo/2024AO18
Jaydeep Tank ,
Sanjay Gupte ,
Purna Chandra Mahapatra ,
Jayanthi Reddy ,
Pratima Mittal ,
Ashish Kumar Mukhopadhyay ,
Lila Vyas ,
Achla Batra ,
Mahesh Gupta ,
Sunita Tandulwadkar ,
Sunita Chandra ,
Vidya Bhat ,
Kawita Bapat ,
Parikshit Tank ,
Ketan Kulkarni ,
Onkar Swami
Visualizações504
Abstract

Objective:

Despite the literature on dydrogesterone, studies on dydrogesterone utilization patterns are largely lacking in Indian patients.

Methods:

This was a multi-center, retrospective, observational, cross-sectional, and descriptive study across 817 centers in India. Data of patients who received dydrogesterone in past and provided consent for future use of their medical record for research purpose was were retrieved and analyzed.

Results:

Data of 7287 subjects (aged 29.55±4.84 years) was analyzed. Threatened abortion was the most common indication for which the subjects received dydrogesterone (46.9%) followed by recurrent pregnancy loss. Polycystic ovary syndrome (PCOS), thyroid disorders and anemia were the most common comorbid conditions and prior pregnancy loss, advanced maternal age and obesity were the most common risk factors seen in subjects who received dydrogesterone. Total 27.5% of subjects received a loading dose of dydrogesterone, and majority (64%) received 40 mg as loading dose. 10 mg dose was used as maintenance or regular dose in 81.4% of the subjects. Twice daily (BID) was the most common dosing frequency (66.6%). The most common concomitant medications being taken by the subjects on dydrogesterone included folic acid (45.1%), iron supplements (30.3%) and calcium and vitamin D3 supplements (25.5%). Another progesterone preparation (oral, injection, vaginal, tubal) other than dydrogesterone was used concurrently in 7.8% of subjects.

Conclusion:

The study helped to identify the patient population that is benefitted by dydrogesterone and the preferred indications, risk factors, comorbid conditions and concomitant medication used in this patient population at real-life scenario.

Palavras-chave: Comorbid conditions Concomitant medications dydrogesterone Gynecological conditions Indian women Risk factors Threatened abortion Utilization pattern
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Original Article
Assessment of sexual and body esteem in postpartum women with or without perineal laceration: a cross-sectional study with cultural translation and validation of the Vaginal Changes Sexual and Body Esteem Scale
Revista Brasileira de Ginecologia e Obstetrícia. 2024;46:e-rbgo35
09/04/2024

Visualizações500

This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Resumo
Original Article
Assessment of sexual and body esteem in postpartum women with or without perineal laceration: a cross-sectional study with cultural translation and validation of the Vaginal Changes Sexual and Body Esteem Scale
Revista Brasileira de Ginecologia e Obstetrícia. 2024;46:e-rbgo35
09/04/2024
DOI 10.61622/rbgo/2024rbgo35
Renata Stefânia Olah de Souza ,
Adriana Gomes Luz ,
Ruth Zielinski ,
Luis Otavio Zanatta Sarian ,
Cassia Raquel Teatin Juliato ,
Lucia Alves da Silva Lara ,
Luiz Gustavo Oliveira Brito
Visualizações500
Objective:

We aimed to translate and determine cultural validity of the Vaginal Changes Sexual and Body Esteem Scale (VSBE) for Brazilian Portuguese language in postpartum women who underwent vaginal delivery with or without perineal laceration and cesarean section.

Methods:

A cross-sectional study conducted virtually, with online data collection through a survey with 234 postpartum women of 975 that were invited. Clinical, sociodemographic, and psychometric variables from the VSBE questionnaire were analyzed (content validity index, internal consistency, test-retest reliability, construct/structural and discriminant validity). Multivariate analysis was performed to explore associated factors with the presence of perineal laceration.

Results:

One-hundred fifty-eight women experienced vaginal delivery, of which 24.79% had an intact perineum, 33.33% had perineal laceration, and 9.4% underwent episiotomy; and 76 participants had cesarean sections. Women with perineal laceration were older, presented dyspareunia and previous surgeries than women without perineal laceration (p<0.05). For VSBE, a high internal consistency (Cronbach's α > 0.7) was observed, but it did not correlate with Body Attractiveness Questionnaire and Female Sexual Function Index; however, it correlated with the presence of women sutured for perineal laceration. Moreover, VSBE presented good structural validity with two loading factors after exploratory factor analysis. VSBE also demonstrated discriminant validity between the presence or absence of perineal laceration. The presence of urinary incontinence (UI) (OR=2.716[1.015-4.667];p=0.046) and a higher VSBE total score (OR=1.056[1.037-1.075];p<0.001) were the only factors associated with perineal laceration.

Conclusion:

Vaginal Changes Sexual and Body Esteem Scale demonstrated appropriate translation and good internal consistency, discriminant/construct validity and reliability. Vaginal Changes Sexual and Body Esteem Scale total score and presence of UI were associated with women that underwent perineal laceration.

Palavras-chave: Cesarean section Postpartum Self concept Sexuality Vaginal delivery
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This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Case Report
Identification of a rare copy number polymorphic gain at 3q12.2 with candidate genes for familial endometriosis
- Flávia Gaona Oliveira ,
- Júlio Cesar Rosa-e-Silva ,
- Alexandra Galvão Gomes ,
- Juliana Dourado Grzesiuk ,
- Thiago Vidotto ,
- Lúcia Martelli
Revista Brasileira de Ginecologia e Obstetrícia. 2024;46:e-rbgo12
00/00/2024

Visualizações490

This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Resumo
Case Report
Identification of a rare copy number polymorphic gain at 3q12.2 with candidate genes for familial endometriosis
Revista Brasileira de Ginecologia e Obstetrícia. 2024;46:e-rbgo12
00/00/2024
DOI 10.61622/rbgo/2024CR12
Flávia Gaona Oliveira ,
Júlio Cesar Rosa-e-Silva ,
Alexandra Galvão Gomes ,
Juliana Dourado Grzesiuk ,
Thiago Vidotto ,
Jeremy Andrew Squire ,
Rodrigo Alexandre Panepucci ,
Juliana Meola ,
Lúcia Martelli
Visualizações490
Abstract

Endometriosis is a complex disease that affects 10-15% of women of reproductive age. Familial studies show that relatives of affected patients have a higher risk of developing the disease, implicating a genetic role for this disorder. Little is known about the impact of germline genomic copy number variant (CNV) polymorphisms on the heredity of the disease. In this study, we describe a rare CNV identified in two sisters with familial endometriosis, which contain genes that may increase the susceptibility and progression of this disease. We investigated the presence of CNVs from the endometrium and blood of the sisters with endometriosis and normal endometrium of five women as controls without the disease using array-CGH through the Agilent 2x400K platform. We excluded common CNVs that were present in the database of genomic variation. We identified, in both sisters, a rare CNV gain affecting 113kb at band 3q12.2 involving two candidate genes: ADGRG7 and TFG. The CNV gain was validated by qPCR. ADGRG7 is located at 3q12.2 and encodes a G protein-coupled receptor influencing the NF-kappaβ pathway. TFG participates in chromosomal translocations associated with hematologic tumor and soft tissue sarcomas, and is also involved in the NF-kappa B pathway. The CNV gain in this family provides a new candidate genetic marker for future familial endometriosis studies. Additional longitudinal studies of affected families must confirm any associations between this rare CNV gain and genes involved in the NF-kappaβ pathway in predisposition to endometriosis.

Palavras-chave: Array-CGH DNA copy number variations Endometriosis Endometrium genetic Genomic structural variation Heredity Polymorphism
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This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Original Article
Fertility preservation in female cancer patients in Brazil: perceptions and attitudes of infertility specialists
Revista Brasileira de Ginecologia e Obstetrícia. 2024;46:e-rbgo25
09/04/2024

Visualizações481

This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Resumo
Original Article
Fertility preservation in female cancer patients in Brazil: perceptions and attitudes of infertility specialists
Revista Brasileira de Ginecologia e Obstetrícia. 2024;46:e-rbgo25
09/04/2024
DOI 10.61622/rbgo/2024rbgo25
Renata Lack Ranniger ,
Rívia Mara Lamaita ,
Bárbara Flecha D’Abreu ,
Mariana Rodrigues Tolentino ,
Eduardo Batista Cândido ,
Warne Pedro Andrade ,
Angélica Nogueira-Rodrigues ,
Agnaldo Lopes Silva-Filho
Visualizações481
Objective:

Fertility preservation is a priority in oncology for female cancer patients. However, there is a lack of communication between infertility specialists and oncologists. This study aimed to evaluate infertility specialists’ perceptions and experiences regarding fertility preservation.

Methods:

Conduct an online survey to profile infertility specialists. Participants were infertility affiliated with the Brazilian Federation of Gynecology and Obstetrics Associations (FEBRASGO). The specialists received an online survey, which response rate were 30.9%, most of whom were in southern and southeastern. The survey consisted on 14 questions about the infertility specialists’ location, techniques in clinical practice, treatment successful rate, patients idea, etc.

Results:

The average experience in human reproduction were 15.5 ± 10.2 years (mean ± standard deviation, range 1-40). Among reproductive-aged female cancer patients recommended for fertility preservation, 60.3 ± 28.8% (range 10-100%) underwent preservation procedures. Main barriers were cost (41%), oncologists’ knowledge or acceptance (35%) and accessibility (9%). Most infertility specialists (58%) considered 40 years the limit for fertility preservation. Leukemia, lymphoma, breast and ovarian cancers were prioritized for fertility preservation, while lung, thyroid, gastric, and brain cancers were less relevant.

Conclusion:

This is the first Brazilian study about infertility specialists’ perceptions on oncology patients access to fertility preservation. These patients primarily receive treatment in the public health system, while infertility specialists mainly work in the private healthcare. This healthcare mode is currently fragmented, but integrating these experts is enhancing patient access to fertility preservation. Studies on this topic are still warranted.

Palavras-chave: attitudes Fertility Fertility preservation gynecologists health knowledge Neoplasms Oncologists Oocyte retrieval practice Reproduction surveys and questionnaires
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This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Original Article
Validation of the Brazilian 10-item Cervantes Scale for the assessment of menopausal symptoms
Revista Brasileira de Ginecologia e Obstetrícia. 2024;46:e-rbgo7
00/00/2024

Visualizações462

This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Resumo
Original Article
Validation of the Brazilian 10-item Cervantes Scale for the assessment of menopausal symptoms
Revista Brasileira de Ginecologia e Obstetrícia. 2024;46:e-rbgo7
00/00/2024
DOI 10.61622/rbgo/2024AO07
Mona Lúcia Dall’Agno ,
Charles Francisco Ferreira ,
Fernanda Vargas Ferreira ,
Pedro do Valle Teichmann ,
Jéssica Zandoná ,
Faustino Ramón Pérez-López ,
Maria Celeste Osório Wender
Visualizações462
Abstract

Objective:

To validate the 10-item Cervantes Scale (CS-10) among Brazilian women.

Methods:

This is a cross-sectional observational study involving women in the community aged 40–55 years in the Southern region of Brazil. They completed a general health, habits and socio-demographic questionnaire, the CS-10 and the Women’s Health Questionnaire (WHQ). Women unable to understand the survey, not consenting to participate, or having incapacity imposing difficulties during the completion of the questionnaire were excluded. A Confirmatory Factor Analysis (CFA) was conducted with the AMOS 16.0 software. Chi-square of degrees of freedom (χ2/df), the Comparative Fit Index (CFI), the Tucker-Lewis Index (TLI) and the Root-Mean-Square Error of Approximation (RMSEA) were used as indices of goodness of fit. Cronbach’s alpha coefficient was used for internal consistency.

Results:

A total of 422 women were included (premenopausal n=35, perimenopausal n=172, postmenopausal n=215). The CFA for the CS-10 showed a good fit (χ²/df=1.454, CFI=0.989; TLI=0.985; RMSEA=0.033; CI 90%=0.002-0.052; PCLOSE=0.921; Model p=0.049). Good reliability was established in CS-10 and WHQ (Cronbach’s alpha=0.724). Postmenopausal women had higher total CS-10 scores (p≤0.0001), reflecting worse quality of life (QoL) related to menopause symptoms and confirming the greater symptomatology evaluated by high total scores for WHQ found in this population when compared to those in the premenopausal period (p=0.041).

Conclusion:

The CS-10 is a consistent tool for health-related QoL in Brazilian mid-aged women.

Palavras-chave: Climacteric Quality of life surveys and questionnaires validation study Women's health
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This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Review Article
A meta-analysis of ferric carboxymaltose versus other intravenous iron preparations for the management of iron deficiency anemia during pregnancy
- Sanjay Gupte ,
- Ashis Mukhopadhyay ,
- Manju Puri ,
- P. M. Gopinath ,
- Reena Wani ,
- Onkar C. Swami
Revista Brasileira de Ginecologia e Obstetrícia. 2024;46:e-rbgo21
15/03/2024

Visualizações461

This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Resumo
Review Article
A meta-analysis of ferric carboxymaltose versus other intravenous iron preparations for the management of iron deficiency anemia during pregnancy
Revista Brasileira de Ginecologia e Obstetrícia. 2024;46:e-rbgo21
15/03/2024
DOI 10.61622/rbgo/2024AO21
Sanjay Gupte ,
Ashis Mukhopadhyay ,
Manju Puri ,
P. M. Gopinath ,
Reena Wani ,
J. B. Sharma ,
Onkar C. Swami
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Abstract

Objective:

We conducted a meta-analysis of randomized clinical trials evaluating the clinical effects of ferric carboxymaltose therapy compared to other intravenous iron in improving hemoglobin and serum ferritin in pregnant women. We also assessed the safety of ferric carboxymaltose vs. other intravenous iron.

Data source:

EMBASE, PubMed, and Web of Science were searched for trials related to ferric carboxymaltose in pregnant women, published between 2005 and 2021. We also reviewed articles from google scholar. The keywords “ferric carboxymaltose,” “FCM,” “intravenous,” “randomized,” “pregnancy,” “quality of life,” and “neonatal outcomes” were used to search the literature. The search was limited to pregnant women.

Selection of studies:

Studies related to ferric carboxymaltose in pregnancy were scanned. Observational studies, review articles, and case reports were excluded. Randomized studies in pregnant women involving ferric carboxymaltose and other intravenous iron formulations were shortlisted. Of 256 studies, nine randomized control trials were selected.

Data collection:

Two reviewers independently extracted data from nine selected trials

Data synthesis:

The final effect size for increase in hemoglobin after treatment was significant for ferric carboxymaltose vs. iron sucrose/iron polymaltose (standard mean difference 0.89g/dl [95% confidence interval 0.27,1.51]). The final effect size for the increase in ferritin after treatment was more for ferric carboxymaltose vs. iron sucrose/iron polymaltose (standard mean difference 22.53µg/L [-7.26, 52.33]). No serious adverse events were reported with ferric carboxymaltose or other intravenous iron.

Conclusion:

Ferric carboxymaltose demonstrated better efficacy than other intravenous iron in increasing hemoglobin and ferritin levels in treating iron deficiency anemia in pregnant women.

Palavras-chave: Anemia Ferric carboximaltose Ferric oxide ferritin hemoglobin Intravenous iron Iron polymaltose Iron sucrose Iron-deficiency anemia Pregnancy saccharated
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This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Original Article
Screening and prevention of preterm birth: how is it done in clinical practice?
Revista Brasileira de Ginecologia e Obstetrícia. 2024;46:e-rbgo32
09/04/2024

Visualizações451

This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Resumo
Original Article
Screening and prevention of preterm birth: how is it done in clinical practice?
Revista Brasileira de Ginecologia e Obstetrícia. 2024;46:e-rbgo32
09/04/2024
DOI 10.61622/rbgo/2024rbgo32
Roberta Bulsing dos Santos ,
Janete Vettorazzi ,
Marcos Wengrover Rosa ,
Ellen Machado Arlindo ,
Edimárlei Gonsales Valério
Visualizações451
Abstract

Objective:

To ascertain how screening for preterm birth is performed among obstetricians working in public and private practice in a middle-income country.

Methods:

Cross-sectional study of 265 obstetrician-gynecologists employed at public and private facilities. An online questionnaire was administered, with items designed to collect data on prematurity screening and prevention practices.

Results:

The mean age of respondents was 44.5 years; 78.5% were female, and 97.7% had completed a medical residency program. Universal screening (i.e., by ultrasound measurement of cervical length) was carried out by only 11.3% of respondents in public practice; 43% request transvaginal ultrasound if the manual exam is abnormal, and 74.6% request it in pregnant women with risk factors for preterm birth. Conversely, 60.7% of respondents in private practice performed universal screening. This difference in screening practices between public and private practice was highly significant (p < 0.001). Nearly all respondents (90.6%) reported prescribing vaginal progesterone for short cervix.

Conclusion:

In the setting of this study, universal ultrasound screening to prevent preterm birth was used by just over half of doctors in private practice. In public facilities, screening was even less common. Use of vaginal progesterone in cervical shortening was highly prevalent. There is an unmet need for formal protocols for screening and prevention of preterm birth in middle-income settings.

Palavras-chave: attitudes, practice Cervical length measurement gynecologists health knowledge Infant, premature obstetricians Preterm birth Prevention Screening surveys and questionnaires
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This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Abstract

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Objective:

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Validation of the Brazilian 10-item Cervantes Scale for the assessment of menopausal symptoms

Abstract

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Methods:

Results:

Conclusion:

A meta-analysis of ferric carboxymaltose versus other intravenous iron preparations for the management of iron deficiency anemia during pregnancy

Abstract

Objective:

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Selection of studies:

Data collection:

Data synthesis:

Conclusion:

Screening and prevention of preterm birth: how is it done in clinical practice?

Abstract

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Methods:

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Conclusion:

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