Frequency of atypical squamous cells of undetermined significance (ASCUS) for pregnant and non-pregnant women - Revista Brasileira de Ginecologia e Obstetrícia
Revista Brasileira de Ginecologia e Obstetrícia. 2015;37(5):229-232
To compare the frequency of an ASCUS Pap Smear result in pregnant and
non-pregnant women, stratified by age group.
We analyzed the results of 1,336,180 cytopathologyc exams of Pap smears performed
between 2000 and 2009 (ten years) with the purpose of screening for cervical
carcinoma. Comparisons were made between pregnant and non-pregnant women, and the
sample was stratified into three age groups (20-24, 25-29 and 30-34 years). The
χ2 test was used and the magnitude of association was determined by
the by Odds Ratio (OR) with the 95% confidence interval (95%CI).
A Total of 447,489 samples were excluded on the basis of the criteria adopted,
for a total final sample of 37,137 pregnant women and 851,554 non-pregnant women.
An ASCUS result was detected in 1.2% of cases, with a significant difference
between pregnant and non-pregnant women in the age groups of 20-24 years (OR=0.85;
95%CI 0.75-0.97) and 25-29 years (OR=0.78; 95%CI 0.63-0.96). There was no
difference in the group between 30-34 years (OR=0.76; 95%CI 0.57-1.03).
This study suggested that non-pregnant women have a higher frequency of ASCUS,
most evident in the age group of 20 to 29 years. The collection of cervical cancer
screening should not be a compulsory part of the prenatal routine.
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To compare the frequency of an ASCUS Pap Smear result in pregnant and non-pregnant women, stratified by age group.
We analyzed the results of 1,336,180 cytopathologyc exams of Pap smears performed between 2000 and 2009 (ten years) with the purpose of screening for cervical carcinoma. Comparisons were made between pregnant and non-pregnant women, and the sample was stratified into three age groups (20-24, 25-29 and 30-34 years). The χ2 test was used and the magnitude of association was determined by the by Odds Ratio (OR) with the 95% confidence interval (95%CI).
A Total of 447,489 samples were excluded on the basis of the criteria adopted, for a total final sample of 37,137 pregnant women and 851,554 non-pregnant women. An ASCUS result was detected in 1.2% of cases, with a significant difference between pregnant and non-pregnant women in the age groups of 20-24 years (OR=0.85; 95%CI 0.75-0.97) and 25-29 years (OR=0.78; 95%CI 0.63-0.96). There was no difference in the group between 30-34 years (OR=0.76; 95%CI 0.57-1.03).
This study suggested that non-pregnant women have a higher frequency of ASCUS, most evident in the age group of 20 to 29 years. The collection of cervical cancer screening should not be a compulsory part of the prenatal routine.
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