Sister Mary Joseph's nodule: a warning sign for intra-abdominal malignant tumors. A case report - Revista Brasileira de Ginecologia e Obstetrícia

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Sister Mary Joseph’s nodule: a warning sign for intra-abdominal malignant tumors. A case report

The umbilical metastatic tumoral nodule, Sister Mary Joseph’s nodule, is a rare clinical sign indicative of disseminated intra-abdominal tumor, and may be the first evidence of malignancy. The authors report a case of a patient with umbilical metastatic nodule in whom the diagnosis of the primary tumor was possible by immunohistochemistry of the lesion biopsy.

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