New Definition of Fetal Growth Restriction: Consensus Regarding a Major Obstetric Complication - Revista Brasileira de Ginecologia e Obstetrícia

Editorial

New Definition of Fetal Growth Restriction: Consensus Regarding a Major Obstetric Complication

Fetal growth restriction (FGR) affects 5–10% of all pregnancies, and it is the second leading cause of perinatal mortality, accounting for ∼ 30% of stillbirths; it leads to premature births and intrapartum asphyxia. Fetuses with FGR have an increased risk for perinatal morbidity and mortality, impaired neurological and cognitive development during childhood and adolescence, and cardiovascular and endocrine disorders in adulthood.

Fetal growth restriction is characterized by cases wherein the fetus does not achieve full intrauterine growth and development because of impaired placental function. However, in clinical practice, FGR is difficult to define, and there is currently no gold standard for its diagnosis. One of the greatest challenges is the differentiation between small for gestational age (SGA) fetuses, who are constitutionally small and healthy, and restricted fetuses, who present with some degree of placental dysfunction and an increased risk for adverse perinatal outcomes.

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