New Criteria for the Clinical Diagnosis of Hyperandrogenism in Polycystic Ovarian Syndrome and the Risk of Overdiagnosis - Revista Brasileira de Ginecologia e Obstetrícia
Rev Bras Ginecol Obstet. 2019;41(6):361-362
The excess of body hair in women is a frequent problem at the clinic that interferes with their femininity and self-esteem, and requires attention from physicians. Classically, hirsutism is the increase of terminal hair in body regions common in the male pattern. In general, hirsutism is associated with hyperandrogenism, but not in all of the cases. In 30 to 50% of the women with mild symptoms, high androgen levels are undetected.
Polycystic ovarian syndrome (PCOS) is the most common cause of hirsutism and corresponds to three out of every four cases. Adrenal dysfunction (Cushing syndrome and enzymatic deficiencies) is the second cause, followed by hypothyroidism, hyperprolactinemia, and androgen-producing tumors (ovarian or adrenal). Certain drugs, mainly anabolicandrogenic steroids, can determine cutaneous hyperandrogenism. These clinical situations are part of the differential diagnosis of PCOS, since its manifestations are translated by the exacerbation of androgenic action.
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The excess of body hair in women is a frequent problem at the clinic that interferes with their femininity and self-esteem, and requires attention from physicians. Classically, hirsutism is the increase of terminal hair in body regions common in the male pattern. In general, hirsutism is associated with hyperandrogenism, but not in all of the cases. In 30 to 50% of the women with mild symptoms, high androgen levels are undetected.
Polycystic ovarian syndrome (PCOS) is the most common cause of hirsutism and corresponds to three out of every four cases. Adrenal dysfunction (Cushing syndrome and enzymatic deficiencies) is the second cause, followed by hypothyroidism, hyperprolactinemia, and androgen-producing tumors (ovarian or adrenal). Certain drugs, mainly anabolicandrogenic steroids, can determine cutaneous hyperandrogenism. These clinical situations are part of the differential diagnosis of PCOS, since its manifestations are translated by the exacerbation of androgenic action.
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