Comments on: Limitations of HPV DNA Testing in Screening of Cervical Adenocarcinomas - Revista Brasileira de Ginecologia e Obstetrícia

Comments on: Limitations of HPV DNA Testing in Screening of Cervical Adenocarcinomas |

Dear Editor,

I read with great interest the article on HPV DNA testing for cervical cancer screening in Brazil, authored by the Brazilian Association for the Lower Genital Tract Pathology and Colposcopy (ABPTGIC, in the Portuguese acronym). In agreement with the authors, I have found irrefutable evidence sustaining the use of molecular detection of HPV DNA in this setting. However, every method, no matter how innovative or advanced, has limitations. The “Achilles’ heel” of HPV DNA primary screening is the detection of glandular lesions. I found that the manuscript by the ABPTGIC tangentially addressed this issue.

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