Are Endocan Plasma Levels Altered in Preeclampsia? - Revista Brasileira de Ginecologia e Obstetrícia

Letter to the Editor

Are Endocan Plasma Levels Altered in Preeclampsia?

Revista Brasileira de Ginecologia e Obstetrícia. 2021;43(3):232-234

DOI: 10.1055/s-0041-1728661

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Dear Editor,

Our research group has been studying preeclampsia (PE) for over a decade aiming to detect possible blood biomarkers of hemostasis, inflammation, and endothelial dysfunction that could be useful for the diagnosis of PE. Until today, only the onset of hypertension (≥ 140 mmHg systolic or ≥ 90 mmHg diastolic) on or after 20 weeks of gestation in association or not with proteinuria and/or evidences of multisystem impairment (such as renal, liver and neurological dysfunctions) is an acceptable criterion to establish the diagnosis of this gestational disease. It is important to emphasize that PE affects between 2 and 8% of all pregnancies worldwide, an early diagnosis of the disease, before the occurrence of systematic impairment, is still not available, which motivates our arduous search for laboratory markers of PE.

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