Analysis of Urinary Tract Vessels during and after Pregnancy in Rats - Revista Brasileira de Ginecologia e Obstetrícia

Purpose: to evaluate the variations in vascular anatomy by assessing the number of vessels of the proximal and distal urethra, of the vesicourethral canal and of the bladder, during and after pregnancy in rats. Method: thirty female rats, with a positive test for pregnancy, were divided into three groups of 10 animals each: GI – rats on the 10th day of pregnancy; GII – rats on the 20th day of pregnancy; GIII – rats on the 5th day of puerperium; a control group (GIV) composed of 10 rats in the estrous phase. The vessels were stained by the method of Masson and counted with a 25-dot integration ocular, coupled to a light microscope, with an objective of 40X. The studied regions were proximal and distal urethra, vesicourethral canal and bladder. Results: there was no significant variation in the vessel number in the bladder, in the vesicourethral canal and in the proximal urethra during gestation. In the distal urethra of the group IV there were 13.7 vessels, less than that observed in the pregnant groups (20.5 to 24.4 vessels). Conclusion: the pregnant rats had a larger number of vessels in the distal urethra than those in the estrous phase. There were no differences regarding the other sites.