Is Pethidine Safe during Labor? Systematic Review - Revista Brasileira de Ginecologia e Obstetrícia

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Systematic Review

Is Pethidine Safe during Labor? Systematic Review

Revista Brasileira de Ginecologia e Obstetrícia. 2017;39(12):686-691

DOI: 10.1055/s-0037-1604065

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Abstract

Purpose

To verify if pethidine is safe for the conceptus when used during labor.

Methods

Systematic review in the Capes Periodicals/PubMed and MEDLINE/Virtual Health Library (BVS, in the Portuguese acronym) databases.

Results

A total of 17 studies published from January 1st, 2000, to September 2nd, 2016, with a total of 1,688 participants involved were included in the present review. There was no record of conceptus vitality decrease associated with low doses of pethidine being administered to mothers during labor.

Conclusions

Intramuscular (IM) or intravenous (IV) pethidine at low doses, of up to 50 mg, is safe to administer during labor.

Key-words Labor pethidine safety

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EndNote RIS

Electronic Document Format (Vancouver)

Nunes RR, Colares PGB, Montenegro JP. Is Pethidine Safe during Labor? Systematic Review. Revista Brasileira de Ginecologia e Obstetrícia 2017;39(12):686-91.

Electronic Document Format (ABNT)

Nunes, Rogevando Rodrigues; Colares, Paulo Giordano Baima; Montenegro, Juliana Pinto. Is Pethidine Safe during Labor? Systematic Review. Revista Brasileira de Ginecologia e Obstetrícia, v. 39, n. 12, p. 686-691, Dec. 2017.

Electronic Document Format (APA)

Nunes, R. R., Colares, P. G. B., & Montenegro, J. P. (2017). Is Pethidine Safe during Labor? Systematic Review. Revista Brasileira de Ginecologia e Obstetrícia, 39(12), 686-691.

Electronic Document Format (ISO)

Nunes, Rogevando Rodrigues and Colares, Paulo Giordano Baima and Montenegro, Juliana Pinto. Is Pethidine Safe during Labor? Systematic Review. Revista Brasileira de Ginecologia e Obstetrícia [online]. 2017, vol. 39, n. 12, [cited 2024-11-21], pp.686-691. Available from: <https://journalrbgo.org/article/is-pethidine-safe-during-labor-systematic-review/>.
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Fig. 1 | Flow chart of the excluded and selected articles.